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Macrotyl-250 Oral is indicated for the control and treatment of respiratory infections associated with tilmicosin-susceptible micro-organisms such as Mycoplasma spp. Pasteurella multocida, Actinobacillus pleuropneumoniae, Actinomyces pyogenes and Mannheimia haemolytica in calves, chickens, turkeys and swine. FOR MEATS: Calves : 42 days.
Get PriceNicosia International - Offering Niimi Oral 25% (25% Tilmicosin Oral Solution Oral Solution For Veterinary Use), पोल्ट्री दवाएं at Rs 7280/litre in Ludhiana, Punjab. Read about company. Get contact details and address| ID: 22403770262
Get PriceTilmicosin Phosphate Tilmicosin Powder HRK Provide Tilmicosin Phosphate Powder CAS 137330-13-3 Tilmicosin Phosphate Price US 60.00-100.00 Kilogram 1.0 Kilograms (Min Order)
Get Price2007-1-15 · A standard calibration curve was prepared by adding 25 μl of tilmicosin phosphate stan- dard (1 mg/ml in water) to 475 μl antibacterial-free chicken plasma. This was further diluted into antibacterial-free chicken plasma to give 0.05, 0.1, 0.5, 1, 2 and 5 μg/ml.
Get PriceCompared to commercial premix, although the TIL-SLNs did not improve the oral absorption of tilmicosin, the time to reach peak concentration (Tmax) was obviously shortened. After the enteric coating of the granules containing SLNs and P-gp inhibitor of polysorbate-80, the oral absorption of tilmicosin was improved 2.72 fold, and the Tmax was shortened by 2 h.
Get Price2008-11-25 · Tilmicosin is a semi-synthetic macrolide antibiotic synthesized by a chemical modification of a tylosin related compound and has been approved to control the causal agents of respiratory diseases in farm animals, including Gram-positive bacteria, mycoplasma, and some Gram-negative bacteria ( Shryock et al., 2002 ).
Get PriceCAS No. 137330-13-3 High quality Tilmicosin (phosphate) powder with factory price Assay: 98% Appearance: White powder Package: 1kg/bag; 25kg/drum, or as customer's request. Storage: Far from fire and heat, keep in cool place Transportation: DHL, EMS, FedEx, TNT, AIR, SEA Application: Pharma grade & Food grade
Get Price2016-3-22 · No serious adverse influences were observed after oral administration of tilmicosin. The concentration of tilmicosin in plasma was reduced below the LOQ after 72 h. A two-compartment model was used for model fitting from 0 to 72 h. The concentration and time profiles are illustrated in Figure Figure4 4. Pharmacokinetic parameters of tilmicosin in plasma were calculated by model analysis …
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Get Price2021-6-30 · Indications. Macrotyl-250 Oral is indicated for the control and treatment of respiratory infections associated with tilmicosin-susceptible micro-organisms such as Mycoplasma spp. Pasteurella multocida, Actinobacillus pleuropneumoniae, Actinomyces pyogenes and Mannheimia haemolytica in calves, chickens, turkeys and swine.
Get Price25% Tilmicosin Phosphate Solution. This product is indicated for the control and treatment of respiratory infections associated with tilmicosin-susceptible micro-organisms such as Mycoplasma spp. Pasteurella multocida, Actinobacillus pleuropneumoniae, Actinomyces pyogenes and Mannheimia haemolytica in calves, chickens, turkeys and swine.
Get PriceProduct: Tilmi 25% Oral. Description. Tilmicosin is a semi-synthesized macrolide antibiotic used for calves, pigs, turkeys and poultry. It has an in vitro antibacterial spectrum that is predominately gram-positive with activity against certain grm-negative micro-organism. Activity against several Mycoplasma species has also been seen.
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Get PriceNicosia International - Offering Niimi Oral 25% (25% Tilmicosin Oral Solution Oral Solution For Veterinary Use), पोल्ट्री दवाएं at Rs 7280/litre in Ludhiana, Punjab. Read about company. Get contact details and address| ID: 22403770262
Get Price2021-5-4 · Tilmicosin 25% Oral is indicated for the control and treatment of respiratory infections associated with micro-organisms susceptible to tilmicosin, such as: Mycoplasma spp., Pasteurella multocida, Mannheimia haemolytica, Actinomyces pyogenes and …
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Get Price2008-11-25 · Oral toxicity of tilmicosin to adult honeybees was evaluated as described by Alippi et al. (1999). The tilmicosin concentrations tested were 50, 100, 200, and 400 μg a.i./bee. Dimethoate was used as a toxic standard and the non-toxic control was 50% (p/v) sucrose in water solution according to previous experiences (Alippi et al., 1999).
Get PriceThis study aimed to develop nanostructured lipid carriers (NLCs) for improved oral absorption of tilmicosin (TMS) in broilers. Thus, palmitic acid, lauric acid, and stearic acid were selected as solid lipids to formulate TMS-pNLCs, TMS-lNLCs, and TMS-sNLCs, respectively. They showed similar physicochemical properties and meanwhile possessed excellent storage and gastrointestinal stability.
Get PriceEffects of oral administration of tilmicosin on pulmonary inflammation in piglets experimentally infected with Actinobacillus pleuropneumoniae. American Journal of Veterinary Research, 2005. Andre Buret. Justine Cottingham-Leblanc. Jason Fedwick. D. Morck. John Merrill. Paul Dick. Marie-anne Paradis.
Get PriceTilmicosin phosphate 200mg (Potency) Powder TOPONE ® Oral Solution 泰好用 ® 口服液 Treatment of bacterial infection Each ml contains： Tilmicosin phosphate (Equivalent to Tilmicosin) 250 mg (Potency) Liquid Clon ® 10% Powder 咳龍10%散 Each g ®
Get Price2016-3-22 · The aim of this study was to establish antimicrobial susceptibility breakpoints for tilmicosin against Haemophilus parasuis, which is an important pathogen of respiratory tract infections.The minimum inhibitory concentrations (MICs) of 103 H. parasuis isolates were determined by the agar dilution method. The wild type (WT) distribution and epidemiologic cutoff value (ECV) were evaluated …
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Get PriceDosage and administration For oral administration via feed or drinking water. Pigs : 125 g per 100 litres of drinking water during 7 - 10 days. Poultry : 250 g per 100 litres of drinking water during 3 - 5 days.
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Get Price엔로삭신 20％액(Enroxacin 20％ Oral) 003-174 CY 틸미포 200 틸미코신포스페이트 Tilmicosin phosphate 2008.07.28 003-175 스코피린 주(Scopyrin Inj) 스코폴라민+디피론 Scopolamine+Dipyrone 2009.06.23 003-176 린코스타 주(Lincostar Inj.) 2009.06.29
Get Price2018-1-11 · [email protected] 250 mg/ml Concentrate for oral Solution contains tilmicosin. It is a semi-synthetic macrolide antibiotic obtained from tylosin which affects bacterial protein synthesis. [email protected] is registered exclusively for veterinary use and primarily for respiratory diseases associated with Mycoplasma spp. and other bacteria sensitive to
Get Price2021-5-10 · Tilmicozag 250 L is an oral liquid preparation containing Tilmicosin phosphate. This broad spectrum antibiotic is suitable for the treatment of bacterial respiratory diseases and other infections caused by Staphylococcus aureus and Clostridium perfringens.
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Get Price2016-12-16 · Tilmi 25% Oral Tilmicosin 49 T.M.P.S. Inj. Sulphamethoxazole, Trimethoprim 50 ... Amprolium 50% Oral Amprolium 60 Amprolium 250 wsp Amprolium 61 ... Worminex 10% Liquid Albendazole 81 Worminex 300 Albendazole 82 Worminex 2500 Albendazole 83. antiparasitic Bupaject Inj. Buparvaquone 86 ...
Get Price2013-9-9 · Tilmicosin Oral Solution 5412002 M.O.H Lic. No.. MICOJAT-L 120 ml Tilmicosin 25% Oral Solution 120 ml MONTAJAT VETERINARY PHARMACEUTICALS CO. LTD. 2nd Industrial City - P.o. Box 4248, Dammam 31491 Saudi Arabia 3812 3221, FAX: +9663 812 3112 e-mail: [email protected] URL: www.montajat.biz
Get PriceLiquid injection Powder for injection Oral solution Capsule Granule Water soluble powder Premix ... Tilmicosin 25% oral solution. Levamisole hydrochloride 20% oral solution. Cow Premix. Total Feed. ... Albendazole 250 mg bolus. Oxytetracycline hydrochloride 250mg tablet. Tetramisole HCl 600 mg. Ivermectin Tablet 5mg.
Get Price2013-1-16 · Data for tilmicosin phosphate and Micotil 300 Injection are reported as indicated. Oral: Tilmicosin phosphate - Rat (fasted), median lethal dose 855 mg/kg, reduced activity, incoordination, drooping eyelids, soft stools, whole body thin, distended abdomen. Skin: Micotil 300 Injection - Rabbit, 0.5 mL/kg, no deaths or toxicity.
Get Price2017-8-28 · Tilmicosin has an elimination half-life of 29.4 hours in cattle and 34.6 hours in sheep. Time to peak serum concentration after SC administration was 0.5 and 3.9 hours in cattle and sheep, respec-tively [2]. Demographics In this study, there were 250 cases of human exposure to tilmi-cosin a year reported to poison centers in the US; more than 150
Get Price2004-1-1 · We investigated tilmicosin (TIM) metabolism, at 25, 50 or 100. μM, in cultures of primary hepatocytes from rabbits bred commercially for food and in liver microsomes prepared from both untreated and rifampicin (RIF)-treated rabbits.. RIF is a well-known cytochrome P4503A (CYP 3A) inducer in rabbits and most macrolides are known to be substrates of CYP 3A.
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Get PriceOral Liquid Solutions Effective oral antibiotic solutions. ... 250 ml ( MercoCiprof 20 ) to 500 ml (MercoCiprof 10 ) ... MercoMicosin 25% is indicated for the control and treatment of respiratory infections associated with tilmicosin¬susceptible micro-organisms. Dosage. Calves: Twice daily, 1 ml per 20 kg body weight via ...
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Get PriceTilmicosin (250 mg) Supporting Information : Click here to upload a PDF. Catalog Number. 1667370. CAS Number. 108050-54-0. Current Lot. G0H061. Previous Lot.
Get Price2013-1-16 · Data for tilmicosin phosphate and Micotil 300 Injection are reported as indicated. Oral: Tilmicosin phosphate - Rat (fasted), median lethal dose 855 mg/kg, reduced activity, incoordination, drooping eyelids, soft stools, whole body thin, distended abdomen. Skin: Micotil 300 Injection - Rabbit, 0.5 mL/kg, no deaths or toxicity.
Get PriceCAS No. 137330-13-3 Veterinary Tilmicosin Phosphate Powder Assay:77.9% Appearance:pale yellow powder Package:by your need Storage:Store in a cool, dry, well-ventilated warehouse.Transportation:by sea or by air Application:Tilmicosin Phosphate is a macrolide antibiotic , it is the upgrade product of tylosin phosphate and specially used for veterinary.
Get PriceTilmicosin in pigs 433 www.vetsci.org Fig. 1. Histopathological image of pig l ung at 48 h after intranasal inoculation with Haemophilus parasuis (left) or sterilized saline (right). H&E stain. 400×. by oral gavage in a single 40 mg/kg dose. This dose was based on the clinical outcome from a 400 mg/kg feed (about 40 mg/kg body weight ...
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Get PriceOral in drinking water or liquid feed. ... • Vaxsafe® MG (Strain TS-11) is supplied in a plastic peel-top 30ml eyedropper bottle with a rubber stopper and aluminium seal. • Each bottle is supplied with a dropper teat and contains 1000 doses. ... Tilmicosin phosphate 25% w/v.
Get PriceUS5574020A US08/372,697 US37269795A US5574020A US 5574020 A US5574020 A US 5574020A US 37269795 A US37269795 A US 37269795A US 5574020 A US5574020 A US 5574020A Authority US United States Prior art keywords tilmicosin formulation propylene glycol injection concentration Prior art date 1989-09-28 Legal status (The legal status is an assumption and is not a legal conclusion.
Get Price2013-9-9 · Tilmicosin Oral Solution 5412002 M.O.H Lic. No.. MICOJAT-L 120 ml Tilmicosin 25% Oral Solution 120 ml MONTAJAT VETERINARY PHARMACEUTICALS CO. LTD. 2nd Industrial City - P.o. Box 4248, Dammam 31491 Saudi Arabia 3812 3221, FAX: +9663 812 3112 e-mail: [email protected] URL: www.montajat.biz
Get PriceThe aim of this study was to determine the blood and tissue concentrations profile and effect of tilmicosin on some hematological and biochemical parameters in broiler chicken. Fifty clinically healthy Hubbard chickens were orally administered 25 mg/kg BW of tilmicosin once daily for 5 consecutive days. Tissue residues of tilmicosin in slaughtered healthy chicken could not be detected by ...
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Get Price2017-12-1 · A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of a single 40 mg/kg dose. The infected model was established by intranasal inoculation and confirmed by clinical signs, blood biochemistry, and microscopic examinations.
Get PriceAfter the end of the 5th day of repeated oral administration of 25 mg/kg BW of tilmicosin once daily for 5 consecutive days, 5 chickens were slaughtered at 24, 48, 72, 96, and 120 hours after the last dose. From each slaughtered chicken, kidneys, lung, heart, liver, fat, breast muscles, thigh muscles, and skin were taken for drug assay.
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Get Price2021-5-1 · Oral Emulsion: Over-the-Counter (OTC) 250 mL PET Bottle: Dostofarm GmbH: Germany: Broadchem Philippines Biopharma Corporation: Broadchem Philippines Biopharma Corporation: 15 March 2017: 19 March 2022: VR-3558: Gamithromycin (Vet.) ZACTRAN: 150mg mL: Solution for Injection (SC) RX: 100 mL, 250 mL & 500 mL Polypropylene Vials with secondary box ...
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Get PriceTilmicozag 250 L. Tilmicozag 250 L is an oral liquid preparation containing Tilmicosin phosphate. This broad spectrum antibiotic is suitable for the treatment of bacterial respiratory diseases and other infections caused by Staphylococcus aureus and Clostridium perfringens. Product Code: 21.P5.98100.
Get PriceMACROTYL-250 ORAL . Oral solution. Tilmicosin (as phosphate) 250 mg/ml. more. MACROTYL-300. Solution for injection. Tilmicosin 300 mg/ml. more. PENSTREP 400. Solution for injection. Procaine penicillin G 200 000 IU/ml, Dihydrostreptomycin 200 mg/ml. more. TIAMULIN INJECTION. Solution for …
Get Price2020-3-11 · TILMICOSIN PHOSPHATE 137330-13-3 25 ... Physical state Liquid. Form Liquid. Color Yellow to Amber. Odor Sweet. Pungent. ... Oral LD50 Rat 855 mg/kg (fasted) (Tilmicosin Phosphate) TILMICOSIN PHOSPHATE (CAS 137330-13-3) Dermal Acute LD Rabbit > 5000 mg/kg Inhalation LC50 Rat 3800 mg/m3, 4 h
Get Price2016-12-16 · Tilmi 25% Oral Tilmicosin 49 T.M.P.S. Inj. Sulphamethoxazole, Trimethoprim 50 ... Amprolium 50% Oral Amprolium 60 Amprolium 250 wsp Amprolium 61 ... Worminex 10% Liquid Albendazole 81 Worminex 300 Albendazole 82 Worminex 2500 Albendazole 83. antiparasitic Bupaject Inj. Buparvaquone 86 ...
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Get Price2014-1-1 · 2.1. Drug (Tilmicosin). Tilmicosin was obtained as an oral solution from Kepro Company for veterinary products (Holland) under a trade name (Tilmi 25% oral solution). Each mL contains 250 mg of tilmicosin (as tilmicosin phosphate). 2.2. Experimental Chicken.
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Get PriceSingle Oral Administration of Tilmicosin in Healthy Broiler Chickens. The mean serum concentrations of tilmicosin at different time intervals following single oral dose (20 mg.kg-1 body weights) in broiler chickens are tabulated in Table (2). The drug was firstly detected (0.19±0.01µg/ml) after 15 minutes and the peak serum concentration (0.85±0.02µg/ml) was reached at 2 hours post drug ...
Get PriceA comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of a single 40 mg/kg dose. The infected model was established by intranasal inoculation and confirmed by clinical signs, blood biochemistry, and microscopic examinations.
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Get PriceIntracellular Accumulation, Subcellular Distribution, and Efflux of Tilmicosin in Bovine Mammary, Blood, and Lung Cells. Bernard Scorneaux. ... Effects of oral administration of tilmicosin on pulmonary inflammation in piglets experimentally infected with Actinobacillus pleuropneumoniae.
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Get PriceBirds from groups IT1-IT4 were given tilmicosin oral solution incorporated at 50, 100, 200, or 300 mg/li-ter, respectively, from 8 to 13 days of age. Efficacy parameters. Birds were examined daily following challenge. Mortality was recorded. On days 13, 16, and 20, the respiratory signs (depression, re-cumbency, sneezing and snoring, dyspnea ...
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Get Price2018-12-15 · Original Article Preparation and Characterization of Three Tilmicosin-loaded Lipid Nanoparticles: Physicochemical Properties and in-vitro Antibacterial Activities Alwan Al-Qushawi a, Ali Rassouli , Fatemeh Atyabi b*, Seyed Mostafa Peighambaric, Mehdi Esfandyari-Maneshd, Gholam Reza Shamsa and Azam Yazdani c aDepartment of Pharmacology, Faculty of Veterinary Medicine, …
Get Price2017-7-24 · Tilmicosin (CAS 108050-54-0) LD Rabbit Dermal Acute > 5000 mg/kg LC50 Rat Inhalation 3800 mg/m3, 4 h TILMICOSIN PHOSPHATE (CAS 137330-13-3) LD Rabbit Dermal Acute > 5000 mg/kg LC50 Rat Inhalation 3800 mg/m3, 4 h LD50 Rat Oral 855 mg/kg (fasted) LD50 Rat Other > 185 mg/kg Subcutaneous: coma, lethargy, incoordination, reduced activity.
Get PriceIntroduction. In poultry, antibiotics and antiparasitics are used extensively for disease prevention and treatment. In the United States, antibiotics are also used for growth promotion, although this type of use has been prohibited in the European Union since 2006 (Donoghue, 2003; Castanon, 2007; Companyo et al., 2009).Edible tissues containing veterinary drug residues can pose risks to human ...
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Get PriceSaunders Handbook of Veterinary Drugs, 4th Edition includes entries for 550 drugs, with convenient appendices summarizing clinically relevant information at a glance. New to this edition are 25 new drug monographs and easy access to drug content on any mobile device.
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